Zhang, Shi-Qi; Guo, Bin; Xu, Ze; Li, Hong-Xi; Li, Hai-Yan; Lang, Jian-Ping published the artcile< Ligand-controlled phosphine-free Co(II)-catalysed cross-coupling of secondary and primary alcohols>, Application of C7H9NO, the main research area is ketone preparation; primary alc secondary cross coupling cobalt catalyst; aryl quinoline preparation; amino alc secondary cross coupling cobalt catalyst.
Cobalt(II) complexes (5 mol% Co) bearing phosphine-free N N N pincer ligands efficiently catalyze C-C coupling of secondary and primary alcs. to selectively form α-alkylated ketones with a good functional group compatibility using NaOH (20 mol%) as a base at 120 °C. The NH group on the N N N-Co(II) precatalyst controlled the activity and selectivity. This simple catalytic system was also involved in the synthesis of 2-aryl quinolines, e.g., I, via the dehydrogenative annulation of 2-aminobenzyl alcs. with secondary alcs.
Tetrahedron published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application of C7H9NO.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts