Thane, Taylor A.; Jarvo, Elizabeth R. published the artcile< Ligand-Based Control of Nickel Catalysts: Switching Chemoselectivity from One-Electron to Two-Electron Pathways in Competing Reactions of 4-Halotetrahydropyrans>, Formula: C4H8O, the main research area is cyclopropylethanol preparation chemoselective; halotetrahydropyran cross electrophile coupling nickel phosphine catalyst; alkyl tetrahydropyran preparation chemoselective; halo tetrahydropyran reduction nickel amine catalyst.
A ligand-based modulation of catalyst preference for one- or two-electron pathways employing 4-halotetrahydropyrans I (Ar = 2-naphthyl, 4-phenylphenyl) as model substrates that can undergo divergent reaction pathways was evaluated. Chemoselectivity for one- or two-electron oxidative addition is predicted by ligand class. Phosphine-ligated nickel catalysts favor closed-shell oxidative addition In contrast, nitrogen-ligated nickel catalysts prefer the one-electron pathway, initiating with halogen atom transfer.
Organic Letters published new progress about Bond activation catalysts (C-O, C-X). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Formula: C4H8O.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts