Singh, Yashapal; Demchenko, Alexei V. published the artcile< Koenigs-Knorr Glycosylation Reaction Catalyzed by Trimethylsilyl Trifluoromethanesulfonate>, Electric Literature of 4064-06-6, the main research area is oligosaccharide preparation Koenigs Knorr glycosylation trimethylsilyl trifluoromethanesulfonate catalyst; Koenigs-Knorr reaction; carbohydrates; glycosidation; synthetic methods.
The discovery that traditional silver(I)-oxide-promoted glycosidations of glycosyl bromides (Koenigs-Knorr reaction) can be greatly accelerated in the presence of catalytic trimethylsilyl trifluoromethanesulfonate (TMSOTf) is reported. The reaction conditions are very mild that allowed for maintaining a practically neutral pH and, at the same time, providing high rates and excellent glycosylation yields. In addition, unusual reactivity trends among a series of differentially protected glycosyl bromides were documented. In particular, benzoylated α-bromides were much more reactive than their benzylated counterparts under these conditions.
Chemistry – A European Journal published new progress about Cooperative phenomena (catalysis). 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Electric Literature of 4064-06-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts