Shui, Hongling; Zhong, Yuhong; Ouyang, Lu; Luo, Nianhua; Luo, Renshi published the artcile< Iridium-Catalyzed Acceptorless Dehydrogenative Coupling of 2-Aminoarylmethanols with Amides or Nitriles to Synthesize Quinazolines>, Application In Synthesis of 5344-90-1, the main research area is quinazoline preparation; aminoarylmethanol amide nitrile acceptorless dehydrogenative coupling iridium catalyst.
An efficient iridium-catalyzed acceptorless dehydrogenative coupling (ADC) reaction for the preparation of various quinazolines from 2-aminoarylmethanols and amides or nitriles had been developed. A wide range of substituted 2-aminobenzyl alcs. and (hetero)aryl or alkyl benzamides and nitriles were well compatible to afford various quinazolines in excellent yields. Merits of this new strategy are the high atom-economy, mild reaction conditions, and simple operation, and the methodol. is suitable for a variety of substrates.
Synthesis published new progress about Amides Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application In Synthesis of 5344-90-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts