Computed Properties of C8H9ClO2On May 8, 1998 ,《Microbiological transformations. Part 39: Determination of the regioselectivity occurring during oxirane ring opening by epoxide hydrolases: a theoretical analysis and a new method for its determination》 appeared in Tetrahedron: Asymmetry. The author of the article were Moussou, Philippe; Archelas, Alain; Baratti, Jacques; Furstoss, Roland. The article conveys some information:
New equations as well as a new method were devised allowing for the total determination of the regioselectivity of biohydrolysis of a racemic epoxide by an epoxide hydrolase. This determination is achievable by simply studying the racemic epoxide as a substrate. Depending on the enantioselectivity (E value) and the regioselectivity involved, the absolute configuration as well as the enantiopurity of the residual epoxide and of the formed diol appear to be highly variable. For a specific enzyme/substrate couple, the yield and enantiopurity of the less reactive (remaining) epoxide – and thus the possibility to prepare it in enantiopure form – exclusively depend upon the enzyme enantioselectivity. On the other hand, the ee of the formed diol depends upon the enantioselectivity and regioselectivity of the oxirane ring opening. A theor. anal. based on the material balance, as well as several practical examples, are provided to illustrate the various possibilities of such biohydrolysis.(1S)-1-(2-chlorophenyl)ethane-1,2-diol(cas: 133082-13-0Computed Properties of C8H9ClO2) was used in this study.
(1S)-1-(2-chlorophenyl)ethane-1,2-diol(cas: 133082-13-0) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains.Computed Properties of C8H9ClO2 The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.
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