Lutz, Marius D. R.; Gasser, Valentina C. M.; Morandi, Bill published the artcile< Shuttle arylation by Rh(I) catalyzed reversible carbon-carbon bond activation of unstrained alcohols>, Electric Literature of 76-84-6, the main research area is tertiary alc green preparation crystal structure mol; triaryl alc ketone bond activation rhodium catalyst.
Herein, a rhodium(I)-catalyzed shuttle arylation cleaving the C(sp2)-C(sp3) bond in unstrained triaryl alcs. via a redox-neutral β-carbon elimination mechanism was reported. A selective transfer hydrocarbylation of substituted (hetero)aryl groups from tertiary alcs. to ketones was realized, employing benign alcs. as latent C-nucleophiles. All preliminary mechanistic experiments support a reversible β-carbon elimination/migratory insertion mechanism. In a broader context, this novel reactivity offers a new platform for the manipulation of tertiary alcs. in catalysis.
Chem published new progress about Bond activation. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Electric Literature of 76-84-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts