Lasa, Aide; Auguste, Manon; Lema, Alberto; Oliveri, Caterina; Borello, Alessio; Taviani, Elisa; Bonello, Guido; Doni, Lapo; Millard, Andrew D.; Bruto, Maxime; Romalde, Jesus L.; Yakimov, Michail; Balbi, Teresa; Pruzzo, Carla; Canesi, Laura; Vezzulli, Luigi published the artcile< A deep-sea bacterium related to coastal marine pathogens>, Quality Control of 87-73-0, the main research area is Vibrio genome sequence pathogenicity coastal marine pathogen.
Evolution of virulence traits from adaptation to environmental niches other than the host is probably a common feature of marine microbial pathogens, whose knowledge might be crucial to understand their emergence and pathogenetic potential. Here, we report genome sequence anal. of a novel marine bacterial species, Vibrio bathopelagicus sp. nov., isolated from warm bathypelagic waters (3309 m depth) of the Mediterranean Sea. Interestingly, V. bathopelagicus sp. nov. is closely related to coastal Vibrio strains pathogenic to marine bivalves. V. bathopelagicus sp. nov. genome encodes genes involved in environmental adaptation to the deep-sea but also in virulence, such as the R5.7 element, MARTX toxin cluster, Type VI secretion system and zinc-metalloprotease, previously associated with Vibrio infections in farmed oysters. The results of functional in vitro assays on immunocytes (haemocytes) of the Mediterranean mussel Mytilus galloprovincialis and the Pacific oyster Crassostrea gigas, and of the early larval development assay in Mytilus support strong toxicity of V. bathopelagicus sp. nov. towards bivalves. V. bathopelagicus sp. nov., isolated from a remote Mediterranean bathypelagic site, is an example of a planktonic marine bacterium with genotypic and phenotypic traits associated with animal pathogenicity, which might have played an evolutionary role in the origin of coastal marine pathogens.
Environmental Microbiology published new progress about Antibiotic resistance. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Quality Control of 87-73-0.
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