In 2018,Organic Chemistry Frontiers included an article by Kuriyama, Masami; Nakashima, Sho; Miyagi, Tsubasa; Sato, Kanako; Yamamoto, Kosuke; Onomura, Osamu. SDS of cas: 27489-62-9. The article was titled 《Palladium-catalyzed chemoselective anaerobic oxidation of N-heterocycle-containing alcohols》. The information in the text is summarized as follows:
The palladium-catalyzed anaerobic oxidation for N-heterocycle-containing alcs. has been developed with chloroarenes as oxidants. In this process, primary and secondary alcs. were selectively oxidized even in the presence of cyclic amines as well as heteroarenes, and primary, secondary, and tertiary amino groups were found to be well tolerated. Moreover, a gram-scale chemoselective oxidation was achieved in addition to a double oxidation of a diamino diol. In the experimental materials used by the author, we found trans-4-Aminocyclohexanol(cas: 27489-62-9SDS of cas: 27489-62-9)
trans-4-Aminocyclohexanol(cas: 27489-62-9) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.SDS of cas: 27489-62-9
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts