Iyer, Gayatri R.; Wigginton, Janis; Duren, William; LaBarre, Jennifer L.; Brandenburg, Marci; Burant, Charles; Michailidis, George; Karnovsky, Alla published the artcile< Application of differential network enrichment analysis for deciphering metabolic alterations>, Related Products of 87-73-0, the main research area is metabolome glutathione type 1 2 diabetes pregnancy; differential networks; enrichment analysis; metabolic disorders; metabolomics and lipidomics; partial correlation networks.
Modern anal. methods allow for the simultaneous detection of hundreds of metabolites, generating increasingly large and complex data sets. The anal. of metabolomics data is a multi-step process that involves data processing and normalization, followed by statistical anal. One of the biggest challenges in metabolomics is linking alterations in metabolite levels to specific biol. processes that are disrupted, contributing to the development of disease or reflecting the disease state. A common approach to accomplishing this goal involves pathway mapping and enrichment anal., which assesses the relative importance of predefined metabolic pathways or other biol. categories. However, traditional knowledge-based enrichment anal. has limitations when it comes to the anal. of metabolomics and lipidomics data. We present a Java-based, user-friendly bioinformatics tool named Filigree that provides a primarily data-driven alternative to the existing knowledge-based enrichment anal. methods. Filigree is based on our previously published differential network enrichment anal. (DNEA) methodol. To demonstrate the utility of the tool, we applied it to previously published studies analyzing the metabolome in the context of metabolic disorders (type 1 and 2 diabetes) and the maternal and infant lipidome during pregnancy.
Metabolites published new progress about Alditols, esters Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Related Products of 87-73-0.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts