Han, Youngjin; Jo, HyunA; Cho, Jae Hyun; Dhanasekaran, Danny N.; Song, Yong Sang published the artcile< Resveratrol as a tumor-suppressive nutraceutical modulating tumor microenvironment and malignant behaviors of cancer>, Electric Literature of 501-36-0 , the main research area is review resveratrol anticancer tumor microenvironment hypoxia oxidative stress cancer; cancer; chemoresistance; metastasis; resveratrol; tumor microenvironment.
A review. Tumor-suppressive effects of resveratrol have been shown in various types of cancer. However, regulation of tumor microenvironment by resveratrol is still unclear. Recent findings suggest resveratrol can potentiate its tumor-suppressive effect through modulation of the signaling pathways of cellular components (fibroblasts, macrophages and T cells). Also, studies have shown that resveratrol can suppress malignant phenotypes of cancer cells acquired in response to stresses of the tumor microenvironment, such as hypoxia, oxidative stress and inflammation. We discuss the effects of resveratrol on cancer cells in stress environment of tumors as well as interactions between cancer cells and non-cancer cells in this review.
International Journal of Molecular Sciences published new progress about Antitumor agents. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, Electric Literature of 501-36-0 .
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