Gauthier, Maxime; Coutrot, Frederic published their research in Chemistry – A European Journal in 2021. The article was titled 《Weinreb Amide, Ketone and Amine as Potential and Competitive Secondary Molecular Stations for Dibenzo-[24]Crown-8 in [2]Rotaxane Molecular Shuttles》.Electric Literature of C6H15NO The article contains the following contents:
This paper reported the synthesis and study of new pH-sensitive DB24C8-based [2]rotaxane mol. shuttles that contain within their axle four potential sites of interaction for the DB24C8: ammonium, amine, Weinreb amide and ketone. In the protonated state, the DB24C8 lay around the best ammonium site. After either deprotonation or deprotonation-then-carbamoylation of the ammonium, different localizations of the DB24C8 were seen, depending on both the number and nature of the secondary stations and steric restriction. Unexpectedly, the results indicated that the Weinreb amide was not a proper secondary mol. station for the DB24C8. Nevertheless, through its methoxy side chain, it slowed down the shuttling of the macrocycle along the threaded axle, thereby partitioning the [2]rotaxane into two translational isomers on the NMR timescale. The ketone was successfully used as a secondary mol. station, and its weak affinity for the DB24C8 was similar to that of a secondary amine. After reading the article, we found that the author used 6-Aminohexan-1-ol(cas: 4048-33-3Electric Literature of C6H15NO)
6-Aminohexan-1-ol(cas: 4048-33-3) may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. It can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine.Electric Literature of C6H15NO
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