Bora, Aditi’s team published research in Journal of Molecular Structure in 2021 | CAS: 126456-43-7

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Formula: C9H11NO

Bora, Aditi; Maiti, Subir Kr; Singh, Anmol; Barman, Pranjit published an article in 2021. The article was titled 《Studies on the effect of remote substituents on the DNA binding activity of novel chiral Schiff bases》, and you may find the article in Journal of Molecular Structure.Formula: C9H11NO The information in the text is summarized as follows:

Three chiral Schiff Bases (1S,2R)-1-(((E)-2-hydroxy-4-methylbenzylidene)amino)-2,3-dihydro-1H-inden-2-ol I (R1 = R3 = H; R2 = Me), (1S,2R)-1-(((E)-3-bromo-5-chloro-2-hydroxybenzylidene)amino)-2,3-dihydro-1H-inden-2-ol I (R1 = Br; R2 = H; R3 = Cl) and (1S,2R)-1-(((E)-2-hydroxy-4-methoxybenzylidene)amino)-2,3-dihydro-1H-inden-2-ol I (R1 = R3 = H; R2 = MeO) were synthesized and characterized by 1H NMR, FT-IR, UV-Vis and elemental anal. (CHN). The crystal structures of I (R1 = R3 = H; R2 = Me) and I (R1 = Br; R2 = H; R3 = Cl) were determined by using single X-ray diffraction crystallog. technique also. It was shown that the remote substituents not only affect the structure of the Schiff bases but also affect the biol. activity. Under physiol. conditions, the interaction of Schiff bases with calf-thymus DNA (CT-DNA) was investigated using fluorescence quenching, UV-Vis spectroscopy and cyclic voltammetry. The order of DNA binding affinity (Kb) calculated from the absorption spectroscopy was: I (R1 = R3 = H; R2 = MeO) > I (R1 = R3 = H; R2 = Me) > I (R1 = Br; R2 = H; R3 = Cl). In the part of experimental materials, we found many familiar compounds, such as (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Formula: C9H11NO)

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Formula: C9H11NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts