Zhai, Pingan; Li, Wenhui; Lin, Jianying; Li, Xing; Wei, Wen-Long; Chen, Wenwen published the artcile< Hydrazones as Substrates in the Synthesis of Isoxazolidines via a KOH-Promoted One-Pot Three-Component Cycloaddition with Nitroso Compounds and Olefins>, Safety of But-3-en-1-ol, the main research area is isoxazolidine preparation diastereoselective; hydrazone nitroso compound olefin one pot three component cycloaddition.
Hydrazones have been employed as the starting materials in a KOH-mediated one-pot three-component cycloaddition with readily accessible nitroso compounds and olefins to construct various isoxazolidines. Compared with diazo compounds as starting materials, this methodol. could afford a wider range of products in good to excellent yields and diastereoselectivities for most substrates, and hydrazones are cheaper, more accessible, and safer substrates. The exptl. study shows that the choice of suitable hydrazones is crucial.
Journal of Organic Chemistry published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Safety of But-3-en-1-ol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts