Yang, Dong; von Krbek, Larissa K. S.; Yu, Le; Ronson, Tanya K.; Thoburn, John D.; Carpenter, John P.; Greenfield, Jake L.; Howe, Duncan J.; Wu, Biao; Nitschke, Jonathan R. published the artcile< Glucose Binding Drives Reconfiguration of a Dynamic Library of Urea-Containing Metal-Organic Assemblies>, Application In Synthesis of 4064-06-6, the main research area is iron urea functionalized ditopic formylpyridine helicate preparation crystal structure; host guest binding activity inclusion iron helicate saccharide mutarotation; dynamic combinatorial library; glucose binding; host-guest systems; metal-organic assemblies; supramolecular chemistry.
A bis-urea-functionalized ditopic subcomponent assembled with 2-formylpyridine and FeII, resulting in a dynamic library of metal-organic assemblies: an irregular FeII4L6 structure and three FeII2L3 stereoisomers: left- and right-handed helicates and a meso-structure. This library reconfigured in response to the addition of monosaccharide derivatives, which served as guests for specific library members, and the rate of saccharide mutarotation was also enhanced by the library. The (P) enantiomer of the FeII2L3 helical structure bound β-D-glucose selectively over α-D-glucose. As a consequence, the library collapsed into the (P)-FeII2L3 helicate following glucose addition The α-D-glucose was likewise transformed into the β-D-anomer during equilibration and binding. Thus, β-D-glucose and (P)-3 amplified each other in the product mixture, as metal-organic and saccharide libraries geared together into a single equilibrating system.
Angewandte Chemie, International Edition published new progress about Crystal structure. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Application In Synthesis of 4064-06-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts