Synthetic Route of C6H15NOIn 2021 ,《Genetically Engineered Polypeptide Adhesive Coacervates for Surgical Applications》 appeared in Angewandte Chemie, International Edition. The author of the article were Sun, Jing; Xiao, Lingling; Li, Bo; Zhao, Kelu; Wang, Zili; Zhou, Yu; Ma, Chao; Li, Jingjing; Zhang, Hongjie; Herrmann, Andreas; Liu, Kai. The article conveys some information:
Adhesive hydrogels have been developed for wound healing applications. However, their adhesive performance is impaired dramatically due to their high swelling on wet tissues. To tackle this challenge, we fabricated a new type of non-swelling protein adhesive for underwater and in vivo applications. In this soft material, the electrostatic complexation between supercharged polypeptides with oppositely charged surfactants containing 3,4-dihydroxylphenylalanine or azobenzene moieties plays an important role for the formation of ultra-strong adhesive coacervates. Remarkably, the adhesion capability is superior to com. cyanoacrylate when tested in ambient conditions. Moreover, the adhesion is stronger than other reported protein-based adhesives in underwater environment. The ex vivo and in vivo experiments demonstrate the persistent adhesive performance and outstanding behaviors for wound sealing and healing. In the experiment, the researchers used 6-Aminohexan-1-ol(cas: 4048-33-3Synthetic Route of C6H15NO)
6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Synthetic Route of C6H15NO
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