In 2018,Sandfort, Frederik; Strieth-Kalthoff, Felix; Klauck, Felix J. R.; James, Michael J.; Glorius, Frank published 《Deaminative Borylation of Aliphatic Amines Enabled by Visible Light Excitation of an Electron Donor-Acceptor Complex》.Chemistry – A European Journal published the findings.Safety of trans-4-Aminocyclohexanol The information in the text is summarized as follows:
A deaminative strategy for the borylation of aliphatic primary amines is described. Alkyl radicals derived from the single-electron reduction of redox-active pyridinium salts, which can be isolated or generated in situ, were borylated in a visible light-mediated reaction with bis(catecholato)diboron. No catalyst or further additives were required. The key electron donor-acceptor complex was characterized in detail by both exptl. and computational investigations. The synthetic potential of this mild protocol was demonstrated through the late-stage functionalization of natural products and drug mols. In the experimental materials used by the author, we found trans-4-Aminocyclohexanol(cas: 27489-62-9Safety of trans-4-Aminocyclohexanol)
trans-4-Aminocyclohexanol(cas: 27489-62-9) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Safety of trans-4-Aminocyclohexanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts