Pan, Li-Chao; Zhu, Yong-Ming; Zhu, Zhen-Yuan; Xue, Wei; Liu, Chun-Yu; Sun, Hui-Qing; Yue-Yin published the artcile< Chemical structure and effects of antioxidation and against α-glucosidase of natural polysaccharide from Glycyrrhiza inflata Batalin>, Related Products of 3458-28-4, the main research area is Glycyrrhiza antioxidant alpha glucosidase natural polysaccharide free radical scavenger; Antioxidant activity; Glycyrrhiza inflata Batalin; Polysaccharide; Structural characterization; Surface plasmon resonance; α-Glucosidase inhibition.
GIBP, a homogeneous polysaccharide extracted from Glycyrrhiza inflata Batalin with a mol. weight 1.96 x 103 kDa, had a triple helix structure, smooth and sheet-like structure. Comprehensive anal. showed that the main chain of GIBP was composed of α-D-1,4 linked glucose, branch points were composed of α-D-1,3,6 and α-D-1,2,3,6 linked glucoses, and side chains were composed of α-D-1,3 and β-D-1,6 linked galactose, β-L-1,2 linked arabinose, α-D-1,3 and β-D-1,3 mannose. The scavenging abilities of GIBP (3 mg/mL) against DPPH· radical, ·OH radical, O2-· radical and ABTS were 50.75 ± 0.13% and 52.32 ± 0.13, 25.84 ± 0.35% and 44.57 ± 0.15% and it also demonstrated an obvious dose-effect relationship. The inhibitory activity of α-glucosidase showed that the inhibitory effect of GIBP was enhanced with the increase of concentration When the concentration reached 6 mg/mL, the inhibition rate of α-glucosidase activity reached 64.77%. And the ka, kd and KD were 6.472 x 104 1/Ms., 2.934 x 10-3 1/s and 4.534 x 10-8 M.
International Journal of Biological Macromolecules published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Related Products of 3458-28-4.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts