Greenhill, John V.; Ramli, Mohamed; Tomassini, Therezinha published the artcile< Reduction of enaminones in the preparation of 3-aminocyclohexanols. Novel preparation of tetronic acid>, Formula: C6H13NO, the main research area is aminocyclohexanol; cyclohexanol amino; reduction enaminone; tetronate.
Reduction of enaminones by Raney Ni gave the corresponding 3-aminocyclohexanols, of which the major product was trans when the substrate was N-unsubstituted. Thus 3-aminocyclohex-2-enone gave 75% of a 59:31 mixture of trans- and cis-3-aminocyclohexanol. The position of attack of NH3 on 2-acetylcyclopentanone and -hexanone was elucidated by reduction of the derived enaminones. The base attacked the side-chain CO in the former case but in the latter the ring CO was attacked. Reduction of 2-(substituted amino)fumaric esters gave enaminone analogs of tetronic acid (I), which on hydrolysis gave I.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 6850-39-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H13NO, Formula: C6H13NO.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts