Gilbreth, Edward; Spann, Shawn; Lavrich, Richard J. published an article in 2022. The article was titled 《Conformational flexibility and hydrogen bonding in 5-aminopentanol》, and you may find the article in Journal of Molecular Spectroscopy.COA of Formula: C3H9NO The information in the text is summarized as follows:
Rotational spectra of two conformers of 5-aminopentanol have been recorded using a Fourier-transform microwave spectrometer. For conformer C-1, eighty-two hyperfine components from the twenty-four a-, b-, and c-type transitions measured were fit to the quadrupole coupling constants, χaa = -2.954(2) MHz, χbb = 2.386(3) MHz. For conformer C-2, the fit of the seventy-six hyperfine components from the twenty-four a- and b-type transitions measured yielded χaa = -3.636(1) MHz and χbb = 2.087(2) MHz. Rotational and centrifugal distortion constants determined from fits of the resulting unsplit line centers to the Watson A-reduction Hamiltonian are A = 3322.169(1) MHz, B = 1958.7382(9) MHz, C = 1402.5957(8) MHz, ΔJ = 0.60(2) kHz, ΔJK = -0.21(8) kHz, ΔK = 0.99(3) kHz, δJ = 0.203(7) kHz, and δK = 1.1(1) kHz for conformer C-1 and A = 3249.2215(6) MHz, B = 2027.9327(3) MHz, C = 1432.5846(3) MHz, ΔJ = 0.545(6) kHz, ΔJK = 0.25(2) kHz, ΔK = 0.39(5) kHz, δJ = 0.18(4) kHz, and δK = 0.96(3) kHz for conformer C-2. The two exptl. conformations are consistent with the two lowest energy ab initio MP2/6-311++G(d,p) structures. Both conformations of 5-aminopentanol are stabilized by an intramol. hydrogen bond from the alc. proton to amino nitrogen. The flexibility introduced by the five carbons in the alkyl group separating the amino and alc. functional groups resulted in the first appearance of multiple low energy conformers being detected relative to the four, three, and two carbons in 4-aminobutanol, 3-aminopropanol, and 2-aminoethanol resp. in which only one exptl. conformation was observed In addition to this study using 3-Aminopropan-1-ol, there are many other studies that have used 3-Aminopropan-1-ol(cas: 156-87-6COA of Formula: C3H9NO) was used in this study.
3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.COA of Formula: C3H9NO
Referemce:
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Alcohols – Chemistry LibreTexts