《Copper-immobilized ionic liquid as an alternative to organic solvents in the one-pot synthesis of bioactive dihydropyrano[2,3-c]pyrazole derivatives》 was published in Applied Organometallic Chemistry in 2020. These research results belong to Ghafuri, Hossein; Kazemnezhad Leili, Maede; Esmaili Zand, Hamid Reza. Category: alcohols-buliding-blocks The article mentions the following:
In this study, a novel Cu-immobilized ionic liquid (IL) I · 3Cu(OAc)3- 3(H2O)was designed, characterized, and employed as both promoter and solvent in the synthesis of some dihydropyrano[2,3-c]pyrazoles II (R = C6H5, 2,4-(Cl)2C6H3, (CH2)2CH3, etc.; R1 = H, 4-O2NC6H4). The synthesized ionic liquid I · 3Cu(OAc)3- 3(H2O) was characterized by 1H NMR, 13C NMR, FTIR, ICP and EDX anal. and showed high catalytic activity to proceed the synthesis of bioactive dihydropyrano[2,3-c]pyrazole derivatives II. This method has the advantage of using the IL as a green medium for the synthesis of the products in high to excellent yields within short reaction times.3-Hydroxybenzaldehyde(cas: 100-83-4Category: alcohols-buliding-blocks) was used in this study.
3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Category: alcohols-buliding-blocks
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts