In 2019,Organic & Biomolecular Chemistry included an article by Fang, Yuanding; Zhao, Rong; Yao, Yuan; Liu, Yang; Chang, Denghu; Yao, Ming; Shi, Lei. Recommanded Product: 2-Hydroxyphenylboronic acid. The article was titled 《Trichloroacetonitrile as an efficient activating agent for the ipso-hydroxylation of arylboronic acids to phenolic compounds》. The information in the text is summarized as follows:
A metal-free and base-free Cl3CCN mediated method was developed for the ipso-hydroxylation of aryl boronic acids to their corresponding phenols which was promoted by a key unstable Lewis adduct intermediate. This transformation was broad functional group tolerance and late-stage functionalization was successful as well. After simple investigation, two pathways (radical/ionic mechanism) were suggested and the beneficial action of blue light needs to be further studied. In the experimental materials used by the author, we found 2-Hydroxyphenylboronic acid(cas: 89466-08-0Recommanded Product: 2-Hydroxyphenylboronic acid)
2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Recommanded Product: 2-Hydroxyphenylboronic acid
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts