Blackmun, Dominique E.; Chamness, Stephen A.; Schindler, Corinna S. published the artcile< Intramolecular, Visible Light-Mediated Aza Paterno-Buchi Reactions of Unactivated Alkenes>, Recommanded Product: But-3-en-1-ol, the main research area is azetidine preparation Aza Paterno Buchi reaction; unactivated alkene intramol visible light Aza Paterno Buchi reaction.
Azetidines are of particular interest in medicinal chem. for their favorable properties, including increased resistance to oxidative metabolism and lower lipophilicity. The recent development of [2 + 2] reactions has significantly expanded the limited repertoire of methods for azetidine synthesis, but access to more complex architectures still requires further development. Herein, authors report a visible-light enabled intramol. [2 + 2] cycloaddition of unactivated alkenes that proved previously unreactive to access tricyclic azetidines with 3D complex structures and high levels of saturation
Organic Letters published new progress about [2+2] Cycloaddition reaction. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Recommanded Product: But-3-en-1-ol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts