The author of 《Molecular capture using the precipitate of creaming-down by (-)-epigallocatechin-3-O-gallate》 were Tsutsumi, Hiroyuki; Sato, Ayano; Fujino, Satoru; Fujioka, Yusuke; Ishizu, Takashi. And the article was published in Chemical & Pharmaceutical Bulletin in 2019. Recommanded Product: 3-Pyridinemethanol The author mentioned the following in the article:
An aqueous solution of equimol. amounts of 2-chloropyrimidine and (-)-epigallocatechin 3-O-gallate (EGCg) afforded a colorless block crystal, which was determined to be a 2 : 2 complex of 2-chloropyrimidine and EGCg by X-ray crystallog. anal. The 2 : 2 complex was formed by the cooperative effect of three intermol. interactions, π-π and CH-π interactions, and intermol. hydrogen bonds. Upon formation of the 2 : 2 complex, a 2-chloropyrimidine mol. was captured by a hydrophobic space formed by the three aromatic rings of A, B, and B’ rings of two EGCg mols. The mol. capture abilities of various heterocyclic compounds using EGCg were evaluated by ratio of the heterocyclic compounds included in the precipitates of complex of EGCg to the heterocyclic compounds used. The amount of the heterocyclic compounds was measured by an integrated value of corresponding proton signals in the quant. 1H-NMR spectrum. The results came from multiple reactions, including the reaction of 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 3-Pyridinemethanol)
3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: 3-Pyridinemethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts