In 2022,Truong, Tan Sang; Retailleau, Pascal; Nguyen, Thanh Binh published an article in Asian Journal of Organic Chemistry. The title of the article was 《TFA/DMSO-Promoted Cross-Dehydrogenative Coupling of Hetaryl Thiols with Indoles: Access to 3-(Hetarylsulfenyl)indole under Mild Conditions》.Safety of Oxetan-3-ol The author mentioned the following in the article:
TFA/DMSO combination was found to efficiently promote the cross-dehydrogenative coupling of a wide range of hetaryl thiols with indole derivatives, leading to 3-(hetarylsulfenyl)indoles in good-to excellent yields under mild heating conditions. Two-fold hetarylsulfenylation of indoles in 2- and 3-positions could be conveniently achieved by simply adapting the molar ratio of the starting materials. After reading the article, we found that the author used Oxetan-3-ol(cas: 7748-36-9Safety of Oxetan-3-ol)
Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Safety of Oxetan-3-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts