Takabatake, Kazuya; Arita, Tomohiro; Nakanishi, Masayoshi; Kuriu, Yoshiaki; Murayama, Yasutoshi; Shimizu, Hiroki; Kudou, Michihiro; Kiuchi, Jun; Kosuga, Toshiyuki; Konishi, Hirotaka; Morimura, Ryo; Shiozaki, Atsushi; Ikoma, Hisashi; Kubota, Takeshi; Fujiwara, Hitoshi; Okamoto, Kazuma; Otsuji, Eigo published the artcile< Impact of inferior mesenteric artery lymph node metastasis on the prognosis of left-sided colorectal cancer>, Safety of Calcium folinate, the main research area is colorectal cancer prognosis inferior mesenteric artery lymph node metastasis; Colorectal cancer; distant lymph node metastasis; inferior mesenteric artery lymph node metastasis; lateral pelvic lymph node metastasis; para-aortic lymph node metastasis; prognosis.
This study aimed to investigate the impact of the inferior mesenteric artery (IMA) lymph node metastasis [IMALN (+)] on prognosis in left-sided colorectal cancer (LCRC). A total of 285 patients with stage III LCRC and 118 patients with stage IV LCRC who underwent resection of primary tumor between 2005 and 2016 were included. IMALN (+) patients (n = 10) had worse overall survival (OS) than patients without IMA lymph node metastasis [IMALN (-); n = 275] in stage III LCRC (p = 0.007). Multivariate anal. revealed that IMALN (+) was a prognostic factor in stage III LCRC (OS, HR = 3.09, p = 0.043). Conversely, there was no difference between the OS of IMALN (+) and stage IV LCRC with distant lymph node metastasis only [stage IV LCRC (LYM); n = 21; p = 0.434]. The prognosis of IMALN (+) was worse than that of IMALN (-); it was similar to that of stage IV LCRC (LYM).
Anticancer Research published new progress about Antitumor agents. 1492-18-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C20H21CaN7O7, Safety of Calcium folinate.
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