Maji, Milan; Chakrabarti, Kaushik; Panja, Dibyajyoti; Kundu, Sabuj published the artcile< Sustainable synthesis of N-heterocycles in water using alcohols following the double dehydrogenation strategy>, HPLC of Formula: 403-41-8, the main research area is quinoline preparation green chem; acridine preparation green chem; naphthyridine preparation green chem; secondary alc amino aralkylalc dehydrogenation oxidative cyclization iridium complex; nitro aralkylalc secondary alc dehydrogenation oxidative cyclization iridium complex.
The present study describes the first example of synthesis of pharmaceutically relevant N-heterocycles like substituted quinolines I (R1 = Ph, 2-pyridinyl, benzo[d][1,3]dioxol-5-yl, 3-phenylpropyl, etc.; R2 = H, Me; R1R2 = -(CH2)3-; R3 = H, Cl, Br, Me; R4 = H; R3R4 = -CH=CH-CH=CH-), acridines e.g., II and 1,8-naphthyridines III in water under air using 2-aminoaryl alcs. or 2-nitroaryl alcs. 2-R5-4-R4-5-R3C6H2CH2OH (R5 = NH2, NO2) and 2-amino-3-pyridinemethanol with secondary alcs. R1CH(OH)CH2R2 and R6(OH) (R6 = cyclopentyl, 1,2,3,4-tetrahydronaphthalen-2-yl, cyclohexyl, cycloheptyl) in presence of a new water soluble Ir-complex e.g., IV·Cl. The viability and efficiency of this approach were demonstrated by the efficient synthesis of biol. active natural product (±)-galipinine and gram scale synthesis of various N-heteroaromatics Several kinetic experiments and DFT calculations were carried out to support the plausible reaction mechanism which disclosed that this system followed a concerted outer sphere mechanism for the dehydrogenation of alcs.
Journal of Catalysis published new progress about Acridines Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, HPLC of Formula: 403-41-8.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts