Recommanded Product: 329735-68-4On September 30, 2021 ,《Novel BIPHEN H2 based P,S-bidentate phosphoramidite ligand in palladium-catalyzed asymmetric allylation》 was published in Mendeleev Communications. The article was written by Gavrilov, Konstantin N.; Chuchelkin, Ilya V.; Zheglov, Sergey V.; Firsin, Ilya D.; Trunina, Valeria M.; Gavrilov, Vladislav K.; Borisova, Nataliya E.; Zimarev, Vladislav S.; Denesh, Andrey A.; Goulioukina, Nataliya S.. The article contains the following contents:
The reaction of P,S-phosphoramidite bearing (Ra)-BIPHEN H2 core and exocyclic amino sulfide as the new ligand with [Pd(ppp-allyl)Cl]2 in the presence of AgBF4 yielded a cationic metallochelate [Pd(ppp-allyl)(L)]BF4. This new chiral inducer provided up to 90% ee in the Pd-mediated allylic substitution reaction of (E)-1,3-diphenylallyl acetate with various C- and N-nucleophiles. In the Pd-catalyzed amination of 2-diethoxyphosphoryl-1-phenylallyl acetate with aniline, ee values up to 57% were achieved. In the part of experimental materials, we found many familiar compounds, such as (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Recommanded Product: 329735-68-4)
(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).Recommanded Product: 329735-68-4
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