In 2019,Chemistry – An Asian Journal included an article by Chulakova, Dilyara R.; Pradipta, Ambara R.; Lodochnikova, Olga A.; Kuznetsov, Danil R.; Bulygina, Kseniya S.; Smirnov, Ivan S.; Usachev, Konstantin S.; Latypova, Liliya Z.; Kurbangalieva, Almira R.; Tanaka, Katsunori. Reference of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol. The article was titled 《Facile Access to Optically Active 2,6-Dialkyl-1,5-Diazacyclooctanes》. The information in the text is summarized as follows:
Herein, the 1,5-diazacyclooctane (1,5-DACO) bearing a chiral auxiliary obtained from the formal [4+4] cycloaddition of N-alkyl-α,β-unsaturated imines was reported. 1,5-DACO could be further derivatized by nucleophilic alkylation to give various chiral substituted 1,5-DACO derivatives I [R = Me, vinyl, Ph, etc.]. The removal of the chiral auxiliary was effectively carried out using hydrogenation over Pearlman’s catalyst. This methodol. allows the production of a broad range of unprecedented optically active 2,6-dialkyl-1,5-DACO II, which could not be accessed by other methods. In the part of experimental materials, we found many familiar compounds, such as (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Reference of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol)
(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Reference of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol
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