Reference of 6-Aminohexan-1-olIn 2020 ,《The breaking beads approach for photocleavage from solid support》 was published in Organic & Biomolecular Chemistry. The article was written by Bakhatan, Yasmeen; Alshanski, Israel; Grunhaus, Dana; Hurevich, Mattan. The article contains the following contents:
Photocleavage from polystyrene beads is a pivotal reaction for solid phase synthesis that relies on photolabile linkers. Photocleavage from intact porous polystyrene beads is not optimal because light cannot penetrate into the beads and the surface area exposed to irradiation is limited. Thus, hazardous, tech. challenging and expensive setups are used for photocleavage from intact beads. We developed a new concept in which grinding the beads during or prior to irradiation is employed as an essential part of the photocleavage process. By grinding the beads we are exposing more surface area to the light source, hence, photocleavage can be performed even using a simple benchtop LED setup. This approach proved very efficient for photocleavage of various model compounds including fully protected oligosaccharides. In the experiment, the researchers used 6-Aminohexan-1-ol(cas: 4048-33-3Reference of 6-Aminohexan-1-ol)
6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Reference of 6-Aminohexan-1-ol
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