Safety of 6-Aminohexan-1-olIn 2022 ,《Study of [2]- and [3]Rotaxanes Obtained by Post-Synthetic Aminolysis of a Kinetically Stable Carbonate-Containing Pseudorotaxane》 appeared in European Journal of Organic Chemistry. The author of the article were Waeles, Philip; Gauthier, Maxime; Coutrot, Frederic. The article conveys some information:
Here the synthesis and study of dibenzo-24-crown-8 (DB24C8)-based [2]- and [3]rotaxanes that contain an ammonium as the best mol. station and carbamate moieties as secondary mol. stations was reported. The common post-interlocking synthesis relies on the aminolysis of the N-succinimidyl carbonate extremity of an activated though insulated pseudorotaxane. The N-succinimidyl carbonate-based thread’s extremity proved to be small enough to allow the slow slippage of the DB24C8 around the thread and large enough to allow insulation of the kinetically stable pseudorotaxane. Due to its sensitivity towards amine compounds, the activated carbonate end of the encircled thread allowed post-interlocking aminolysis-based conversion into mech. interlocked rotaxanes by providing the same way the carbamate secondary station for the DB24C8 in the thread backbone. Translation of the DB24C8 along the threaded axle between the two mol. stations was investigated. In the experiment, the researchers used 6-Aminohexan-1-ol(cas: 4048-33-3Safety of 6-Aminohexan-1-ol)
6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Safety of 6-Aminohexan-1-ol
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