In 2022,Medicine (Philadelphia, PA, United States) included an article by Tang, Haowei; Yuan, Zhi; Li, JingJie; Wang, Qun; Fan, Weijie. Recommanded Product: trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride. The article was titled 《The application of ambroxol hydrochloride combined with fiberoptic bronchoscopy in elderly patients with severe pneumonia: A meta-analysis and systematic review》. The information in the text is summarized as follows:
The role of ambroxol hydrochloride combined with fiberoptic bronchoscopy in elderly patients with severe pneumonia remains unclear, we aimed to analyze this issue to provide evidences into the management of clin. pneumonia. We searched PubMed et al databases up to Oct. 20, 2021 for the randomized controlled trials on the application of ambroxol hydrochloride combined with fiberoptic bronchoscopy in elderly patients with severe pneumonia. Related outcomes were extracted and analyzed. Review Manager 5.3 software was used for data anal. A total of 13 randomized controlled trials involving 1317 elderly patients (559 cases in the ambroxol hydrochloride+fiberoptic bronchoscopy group and 658 cases in the fiberoptic bronchoscopy group) with pneumonia were included. Meta-analyses indicated that the blood oxygen partial pressure [mean difference (MD)=5.75, 95% confidence interval (CI) (3.80, 7.70)], blood oxygen saturation [MD=6.43, 95% CI (4.39, 8.48)], oxygenation index [MD=26.75, 95% CI (14.61, 38.89)] of exptl. group was significantly higher than that of control group (all P001), the incidence of multiple organ failure [odds ratio=0.42, 95% CI (0.31, 0.56), P001], mortality on day 28 [odds ratio=0.44, 95% CI (0.33, 0.59)] of exptl. group was significantly less than that of control group (all P001). The high-dose ambroxol hydrochloride combined with fiberoptic bronchoscopy is beneficial to improve the patients blood gas indicators, and reduce mortality in elderly patients with severe pneumonia. In addition to this study using trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, there are many other studies that have used trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride(cas: 23828-92-4Recommanded Product: trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride) was used in this study.
trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride(cas: 23828-92-4) is a medication indicated to alleviate chest congestion associated with conditions that include bronchitis, pneumonia, bronchospasm asthma, cough, and allergy.Recommanded Product: trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride Preclinically, ambroxol, the active ingredient of Mucosolvan, has been shown to increase respiratory tract secretion.
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