Safety of 2-Aminopropane-1,3-diolIn 2019 ,《Supramolecular Gels Derived from Simple Organic Salts of Flufenamic Acid: Design, Synthesis, Structures, and Plausible Biomedical Application》 was published in ACS Biomaterials Science & Engineering. The article was written by Parveen, Rumana; Jayamma, Bandi; Dastidar, Parthasarathi. The article contains the following contents:
Following supramol. synthon rationale in the context of crystal engineering, a non-steroidal-anti-inflammatory-drug (NSAID) namely Flufenamic acid (FA) and its β-alanine monopeptide derivative (FM) were converted to a series of primary ammonium monocarboxylate (PAM) salts. Majority of the PAM salts (∼90 %) showed gelation with various solvents including water and Me salicylate (important solvents in topical gel formulation). Structure-property correlation studies based on single crystal X-ray diffraction (SXRD) and powder X-ray diffraction (PXRD) data provided intriguing insights into the structure of the gel network. Furthermore, one of the gelator salts (S7) displayed anti-cancer activity on a highly aggressive human breast cancer cell line (MDA-MB-231) as revealed by MTT, PEG2 and cell migration assays. In the part of experimental materials, we found many familiar compounds, such as 2-Aminopropane-1,3-diol(cas: 534-03-2Safety of 2-Aminopropane-1,3-diol)
2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.Safety of 2-Aminopropane-1,3-diol
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