《Chromium-Catalyzed Alkylation of Amines by Alcohols》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Kallmeier, Fabian; Fertig, Robin; Irrgang, Torsten; Kempe, Rhett. HPLC of Formula: 873-75-6 The article mentions the following:
The alkylation of amines by alcs. is a broadly applicable, sustainable, and selective method for the synthesis of alkyl amines, which are important bulk and fine chems., pharmaceuticals, and agrochems. We show that Cr complexes can catalyze this C-N bond formation reaction. We synthesized and isolated 35 examples of alkylated amines, including 13 previously undisclosed products, and the use of amino alcs. as alkylating agents was demonstrated. The catalyst tolerates numerous functional groups, including hydrogenation-sensitive examples. Compared to many other alc.-based amine alkylation methods, where a stoichiometric amount of base is required, our Cr-based catalyst system gives yields higher than 90% for various alkyl amines with a catalytic amount of base. Our study indicates that Cr complexes can catalyze borrowing hydrogen or hydrogen autotransfer reactions and could thus be an alternative to Fe, Co, and Mn, or noble metals in (de)hydrogenation catalysis.(4-Bromophenyl)methanol(cas: 873-75-6HPLC of Formula: 873-75-6) was used in this study.
(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.HPLC of Formula: 873-75-6 It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts