In 2019,Angewandte Chemie, International Edition included an article by Jang, Won Jun; Yun, Jaesook. Application of 78782-17-9. The article was titled 《Catalytic Asymmetric Conjugate Addition of a Borylalkyl Copper Complex for Chiral Organoboronate Synthesis》. The information in the text is summarized as follows:
The authors report the catalytic enantioselective conjugate addition of a borylalkyl Cu nucleophile generated in situ from a 1,1-diborylmethane derivative to α,β-unsaturated diesters. In the presence of a chiral N-heterocyclic carbene (NHC)-Cu catalyst, this method facilitated the enantioselective incorporation of a CH2Bpin moiety at the β-position of the diesters to yield β-chiral alkyl boronates in up to 86% yield with high enantioselectivity. The alkylboron moiety in the resulting chiral diester products was converted into various functional groups by organic transformation of the C-B bond. The experimental process involved the reaction of Bis[(pinacolato)boryl]methane(cas: 78782-17-9Application of 78782-17-9)
Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds. Organoboron compounds have been a cornerstone of synthetic transformations for decades. Areas such as boron-containing catalysts, metalate chemistry, photoredox methods, and boryl anions have brought significant new developments in understanding and provided new reactivity upon.Application of 78782-17-9
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