《Catalytic Acceptorless Dehydrogenation of Aliphatic Alcohols》 was written by Fuse, Hiromu; Mitsunuma, Harunobu; Kanai, Motomu. Quality Control of 6-Aminohexan-1-ol And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:
First acceptorless dehydrogenation of aliphatic secondary alcs., e.g., epiandrosterone to ketones, e.g., androstane-3,17-dion under visible light irradiation at room temperature by devising a ternary hybrid catalyst system comprising a photoredox catalyst, a thiophosphate organocatalyst, and a nickel catalyst has been described. The reaction proceeded through three main steps: hydrogen atom transfer from the α-C-H bond of an alc. substrate to the thiyl radical of the photo-oxidized organocatalyst, interception of the generated carbon-centered radical with a nickel catalyst, and β-hydride elimination. The reaction proceeded in high yield under mild conditions without producing side products (except H2 gas) from various alcs., including sterically hindered alcs., a steroid, and a pharmaceutical derivative This catalyst system also promoted acceptorless cross-dehydrogenative esterification from aldehydes R1CHO (R1 = cyclohexyl, nonyl, 9-[(4-bromophenyl)carbonyloxy]nonyl, etc.) and alcs. like 2,2,2-trichloroethanol and 2,2,2-trifluoroethanol through hemiacetal intermediates. In the experimental materials used by the author, we found 6-Aminohexan-1-ol(cas: 4048-33-3Quality Control of 6-Aminohexan-1-ol)
6-Aminohexan-1-ol(cas: 4048-33-3) may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. It can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine.Quality Control of 6-Aminohexan-1-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts