In 2018,Danon, Jonathan J.; Leigh, David A.; Pisano, Simone; Valero, Alberto; Vitorica-Yrezabal, Inigo J. published 《A Six-Crossing Doubly Interlocked [2]Catenane with Twisted Rings, and a Molecular Granny Knot》.Angewandte Chemie, International Edition published the findings.Safety of 2,6-Pyridinedimethanol The information in the text is summarized as follows:
A mol. 623 link (a six crossing, doubly interlocked, [2]catenane with twisted rings) and a 31#31 granny knot (a composite knot made up of two trefoil tangles of the same handedness) were constructed by ring-closing olefin metathesis of an Fe(II)-coordinated 2×2 interwoven grid. The connections were directed by pendant Ph groups to be between proximal ligand ends on the same faces of the grid. The 623 link was separated from the topoisomeric granny knot by recycling size-exclusion chromatog. The identity of each topoisomer was determined by tandem mass spectrometry and the structure of the 623 link confirmed by x-ray crystallog., which revealed two 82-membered macrocycles, each in figure-of-eight conformations, linked through both pairs of loops. In addition to this study using 2,6-Pyridinedimethanol, there are many other studies that have used 2,6-Pyridinedimethanol(cas: 1195-59-1Safety of 2,6-Pyridinedimethanol) was used in this study.
2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Safety of 2,6-Pyridinedimethanol
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