Cowley, Phillip M.; Baker, James; Buchanan, Kirsteen I.; Carlyle, Ian; Clark, John K.; Clarkson, Thomas R.; Deehan, Maureen; Edwards, Darren; Kiyoi, Yasuko; Martin, Iain; Osbourn, Dawn; Walker, Glenn; Ward, Nick; Wishart, Grant published the artcile< Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists>, Application In Synthesis of 45434-02-4, the main research area is cannabinoid CB antagonist indolecarboxamide preparation pharmacokinetics SAR.
The pharmacokinetic based optimization of a novel series of indole-2-carboxamide antagonists of the cannabinoid CB1 receptor is disclosed. Compound 24 (I) was found to be a highly potent and selective cannabinoid CB1 antagonist with high predicted human oral bioavailability.
Bioorganic & Medicinal Chemistry Letters published new progress about Cannabinoid receptor 1 Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 45434-02-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C5H11NO, Application In Synthesis of 45434-02-4.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts