Boyko, Yaroslav D.’s team published research in Journal of the American Chemical Society in 2021 | CAS: 78782-17-9

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds. Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. This stems from their ease of preparation combined with their ability to undergo a broad range of chemical transformations.COA of Formula: C13H26B2O4

Boyko, Yaroslav D.; Huck, Christopher J.; Ning, Shang; Shved, Alexander S.; Yang, Cheng; Chu, Tiffany; Tonogai, Emily J.; Hergenrother, Paul J.; Sarlah, David published an article in 2021. The article was titled 《Synthetic studies on selective, proapoptotic isomalabaricane triterpenoids aided by computational techniques》, and you may find the article in Journal of the American Chemical Society.COA of Formula: C13H26B2O4 The information in the text is summarized as follows:

The isomalabaricanes comprise a large family of marine triterpenoids with fascinating structures that have been shown to be selective and potent apoptosis inducers in certain cancer cell lines. In this article, we describe the successful total syntheses of the isomalabaricanes Stelletin A, Stelletin E, and Rhabdastrellic acid A, as well as the development of a general strategy to access other natural products within this unique family. High-throughput experimentation and computational chem. methods were used in this endeavor. A preliminary structure-activity relationship study of Stelletin A revealed the trans-syn-trans core motif of the isomalabaricanes to be critical for their cytotoxic activity. In addition to this study using Bis[(pinacolato)boryl]methane, there are many other studies that have used Bis[(pinacolato)boryl]methane(cas: 78782-17-9COA of Formula: C13H26B2O4) was used in this study.

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds. Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. This stems from their ease of preparation combined with their ability to undergo a broad range of chemical transformations.COA of Formula: C13H26B2O4

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