Amouzadeh Tabrizi, Mahmoud; Nazari, Leila; Acedo, Pablo published their research in Sensors and Actuators, B: Chemical in 2021. The article was titled 《A photo-electrochemical aptasensor for the determination of severe acute respiratory syndrome coronavirus 2 receptor-binding domain by using graphitic carbon nitride-cadmium sulfide quantum dots nanocomposite》.Application In Synthesis of 6-Aminohexan-1-ol The article contains the following contents:
Herein, a photoelectrochem. aptasensor for the quant. measurement of the severe acute respiratory syndrome coronavirus-2 receptor-binding domain (Sars-Cov-2 RBD) has been reported for the first time. For this purpose, first, graphitic carbon nitride and (gC3N4) and cadmium sulfide (CdS) quantum dots were fabricated and characterized. After that, gC3N4 and CdS were mixed well. The fabricated nanomaterials were characterized by scanning transmission electron microscopy. Then, the CdS QDs-gC3N4 nanocomposite was added to the solution containing chitosan as an amine-rich polymer to generate a Chitosan/CdS-gC3N4 nanocomposite. Subsequently, the surface of the ITO electrode was modified with Chitosan/CdS-gC3N4. After that, the amine-terminal aptamer probes were immobilized on the surface of the Chitosan/CdS QDs-gC3N4/ITO electrode by using glutaraldehyde as an amine-amine crosslinker. The electrochem. performances of the electrodes were studied using cyclic voltammetry (CV), electrochem. Impedance Spectroscopy (EIS), and photo-electrochem. (PEC). The surface coverage of the immobilized aptamer probe was founded to be 26.2 pmol.cm-2. The obtained results demonstrated that the proposed photo-electrochem. aptasensor can be used for the measurement of Sars-Cov-2 RBD within 0.5-32.0 nM. The limit of detection (LOD) was obtained to be 0.12 nM (at 3σ/slope). The affinity of the Aptamer/Chitosan/CdS QDs-gC3N4/ITO was also founded to be 3.4 nM by using Langmuir-typical adsorption systems. The proposed photo-electrochem. aptasensor was applied for the measurement of the spiked Sars-Cov-2 RBD in human saliva samples at two concentrations The effect of the interfering biomaterials such as human IgG human IgA, human IgM, and human serum albumin was also studied. The experimental process involved the reaction of 6-Aminohexan-1-ol(cas: 4048-33-3Application In Synthesis of 6-Aminohexan-1-ol)
6-Aminohexan-1-ol(cas: 4048-33-3) may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. It can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine.Application In Synthesis of 6-Aminohexan-1-ol
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