Zhou, Siai; Zhong, Xuemei; Guo, Aoxin; Xiao, Qian; Ao, Jiaming; Zhu, Wanmeng; Cai, Hui; Ishiwata, Akihiro; Ito, Yukishige; Liu, Xue-Wei; Ding, Feiqing published the artcile< ZnI2-Directed Stereocontrolled α-Glucosylation>, Category: alcohols-buliding-blocks, the main research area is glycoside preparation disaccharide oligosaccharide stereoselective glycosylation serine; transition state Gibbs free energy electron density stereoselective glycosylation.
Here we report a glucosylation strategy mediated by ZnI2, a cheap and mild Lewis acid, for the highly stereoselective construction of 1,2-cis-O-glycosidic linkages using easily accessible and common 4,6-O-tethered glucosyl donors. The versatility and effectiveness of the α-glucosylation strategy were demonstrated successfully with various acceptors, including complex alcs. This approach demonstrates the feasibility of the modular synthesis of various α-glucans with both linear and branched backbone structures.
Organic Letters published new progress about Disaccharides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts