《The Cascade C-H functionalization with sequential hydroxylation and oxidation through heterogeneous BINAP-copper on hydrotalcite》 was written by Zhang, Qiaohong; Wang, Huibin; Hu, Wenkang; Xu, Xiaqing; Xu, Zhaojun; Chen, Chen; Wang, Dawei. Application of 89466-08-0 And the article was included in Journal of Chemical Technology and Biotechnology in 2020. The article conveys some information:
A cascade C-H hydroxylation and further oxidation process, 2-sulfanylphenols 6-OH-R1C6H3S(R2 C6H4) (R1 = H, 2-Br, 3-Br, 4-CF3, etc.; R2 = H, 2-OMe, 3-OMe, 4-F, etc.) and arylthioquinones I (R3 = H, 2,6-Cl2, 3-Br, 4-tBu, etc.) use the heterogeneous catalyst [Cu(binap)I]2@HT. The catalytic system was tolerant to various substituents including alkyl, alkoxy, ester, halogen or trifluoromethyl on the Ph ring of the thiophenols R1C6H4SH/3-R4OC6H4SH (R4 = H, Me) or arylboronic acids R5B(OH)2 (R5 = Ph, 4-ethoxyphenyl, 2,6-dichlorophenyl, etc.). In addition to electron-donating groups, the products with strong electron-withdrawing groups, such as Me formylate and trifluoromethyl also were achieved with good yields at 90°C for 12h (68% and 66%, resp.). Repeated experiment results showed that the catalyst could be reused at least five times without obvious decrease in catalytic activity. In the experimental materials used by the author, we found 2-Hydroxyphenylboronic acid(cas: 89466-08-0Application of 89466-08-0)
2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Application of 89466-08-0
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