Vezina, Ben; Judd, Louise M.; McDougall, Fiona K.; Boardman, Wayne S. J.; Power, Michelle L.; Hawkey, Jane; Brisse, Sylvain; Monk, Jonathan M.; Holt, Kathryn E.; Wyres, Kelly L. published the artcile< Transmission of Klebsiella strains and plasmids within and between grey-headed flying fox colonies>, Related Products of 87-73-0, the main research area is plasmid transmission Klebsiella Pteropus.
The gray-headed flying fox (Pteropus poliocephalus) is an endemic Australian fruit bat, known to carry zoonotic pathogens. We recently showed they harbor bacterial pathogen Klebsiella pneumoniae and closely related species in the K. pneumoniae species complex (KpSC); however, the dynamics of KpSC transmission and gene flow within flying fox colonies are poorly understood. High-resolution genome comparisons of 39 KpSC isolates from gray-headed flying foxes identified five putative strain transmission clusters (four intra- and one inter-colony). The instance of inter-colony strain transmission of K. africana was found between two flying fox populations within flying distance, indicating either direct or indirect transmission through a common food/water source. All 11 plasmids identified within the KpSC isolates showed 73% coverage (mean) and ≥95% identity to human-associated KpSC plasmids, indicating gene flow between human clin. and gray-headed flying fox isolates. Along with strain transmission, inter-species horizontal plasmid transmission between K. pneumoniae and Klebsiella africana was also identified within a flying fox colony. Finally, genome-scale metabolic models were generated to predict and compare substrate usage to previously published KpSC models, from human and environmental sources. These models indicated no distinction on the basis of metabolic capabilities. Instead, metabolic capabilities were consistent with population structure and ST/lineage.
Environmental Microbiology published new progress about Food. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Related Products of 87-73-0.
Referemce:
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Alcohols – Chemistry LibreTexts