Scott, David E.; Aloisio, Mark D.; Rodriguez, Jose F.; Morimoto, Masato; Hamilton, Robin J.; Brown, Orain; Tykwinski, Rik R.; Stryker, Jeffrey M. published the artcile< Optimizing the Iodide/Iodonium/O2 Oxidation Cycle Enhances the Scope, Selectivity, and Yields of Hydroiodic Acid-Catalyzed Multicomponent Cyclocondensation Reactions>, Category: alcohols-buliding-blocks, the main research area is quinoline preparation; aralkyl aldehyde aniline multicomponent cyclocondensation hydroiodic acid catalyst.
This work establishes that two independent catalytic cycles (H+ and I-/I+) drive such multicomponent cyclocondensation/ oxidation reactions, provided that the oxidant is generated in sufficient concentration to inhibit oxidation of the dihydroquinoline by the intermediate iminium cation. The complementary dual catalytic cycles, when optimized, act in concert to suppress side product formation, which simplifies isolation and purification of the self-aggregating products and increases the efficiency and scope of the Wang-Kozlov multicomponent reaction.
Advanced Synthesis & Catalysis published new progress about Aliphatic aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent) (aryl). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts