The author of 《Concurrent analysis of ambroxol HCl and salbutamol sulphate from tablet formulation by RP-HPLC》 were Panchale, Wrushali A.; Badukle, Neha A.; Sabhadinde, Amar F.; Bakal, Ravindra L.; Manwar, Jagdish V.. And the article was published in GSC Biological and Pharmaceutical Sciences in 2020. Formula: C13H19Br2ClN2O The author mentioned the following in the article:
RP-HPLC method was developed for concurrent anal. of ambroxol HCl and salbutamol sulfate from tablet formulation. Analytes were separated with mobile phase consisting of mixture of methanol and water (0.1% triethylamine) in the ratio 50: 50 at a flow rate of 0.7 mL/min with Nucleosil (4.6 mm I.D x 250 mm) C18 column. The retention time of ambroxol HCl and salbutamol sulfate was found to be 3.61 and 6.20 min, resp. The detection was carried out at 224 nm. The dynamic range for ambroxol HCl and salbutamol sulfate observed was 15-75μg/mL and 1-5μg/mL, resp. The percent recovery obtained for ambroxol HCl and salbutamol sulfate were close to 100%. Obtained statistical data of results was found to satisfactorily.trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride(cas: 23828-92-4Formula: C13H19Br2ClN2O) was used in this study.
trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride(cas: 23828-92-4) is a mucolytic expectorant and a metabolite of bromhexine.Formula: C13H19Br2ClN2O It is used in the treatment of respiratory disorders characterized by viscous or excessive mucus.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts