Kinsinger, Thorsten; Kazmaier, Uli published the artcile< Application of Vinyl Nucleophiles in Matteson Homologations>, Synthetic Route of 76-84-6, the main research area is allyl boronic ester preparation enantioselective; alkyl boronic ester vinyl nucleophile Grignard reagent Matteson homologation.
The Matteson homologation with vinyl nucleophiles was found to be a versatile tool for the synthesis of highly substituted and functionalized allyl boronic esters I (R = phenylethyl, Me, butan-2-yl, etc.), II (R1 = H, Me; R2 = H, Me; R3 = H, Me), III and IV (R4 = Me, Et, n-Pr; R5 = H, Me). High yields and stereoselectivities are obtained with sterically demanding alkyl boronic esters and/or Grignard reagents. With the application of such vinyl Matteson homologations, the polyketide fragment of lagunamide B is synthesized.
Organic Letters published new progress about Boronic acids, esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Synthetic Route of 76-84-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts