《Newly synthesized imino-derivatives analogues of resveratrol exert inhibitory effects in breast tumor cells》 was published in International Journal of Molecular Sciences in 2020. These research results belong to Iacopetta, Domenico; Lappano, Rosamaria; Mariconda, Annaluisa; Ceramella, Jessica; Sinicropi, Maria Stefania; Saturnino, Carmela; Talia, Marianna; Cirillo, Francesca; Martinelli, Fabio; Puoci, Francesco; Rosano, Camillo; Longo, Pasquale; Maggiolini, Marcello. Name: 3,5-Dihydroxybenzaldehyde The article mentions the following:
Breast cancer represents the most frequently diagnosed malignancy in women worldwide. Various therapeutics are currently used in order to halt the progression of breast tumor, even though certain side effects may limit the beneficial effects. In recent years, many efforts have been addressed to the usefulness of natural compounds as anticancer agents due to their low toxicity. Resveratrol, a stilbene found in grapes, berries, peanuts and soybeans, has raised a notable interest for its antioxidant, anti-inflammatory, and antitumor properties. Here, we report the design, the synthesis and the characterization of the anticancer activity of a small series of imino N-aryl-substituted compounds that are analogs of resveratrol. In particular, the most active compound, named 3, exhibited anti-tumor activity in diverse types of breast cancer cells through the inhibition of the human topoisomerase II and the induction of apoptotic cell death. Therefore, the abovementioned compound maybe considered as a promising agent in more comprehensive treatments of breast cancer.3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Name: 3,5-Dihydroxybenzaldehyde) was used in this study.
3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Name: 3,5-Dihydroxybenzaldehyde
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