Hu, Fangzhi; Li, Xinyao; Ding, Zhanshuai; Wang, Liang; Ge, Chunyan; Xu, Lubin; Li, Shuai-Shuai published the artcile< Divergent Synthesis of [3,4]-Fused 3-Alkenyl-Oxindoles via Propargyl Alcohol-Triggered C(sp3)-H Functionalization>, Product Details of C4H8O, the main research area is hydroxy arylethynyl pyrrolidinyl indolinone nucleophile binaphthyldiyl hydrogenphosphate catalyst cyclization; aryl diazatetracyclo hexadeca tetraenone preparation regioselective cascade.
Developed a synthetic strategy for divergent synthesis of diverse types of [3,4]-seven- or six-membered ring-fused 3-alkenyl-oxindoles incorporating benzazepine and significant building blocks from propargyl alcs. via the cascade nucleophilic substitution/site-selective hydride transfer/cyclization process unprecedentedly. Also, a variety of nucleophiles, including H2O, were available for controllable construction of a wide range of conjugated alkenes, conjugated ketones and allyl alcs. encompassing natural products and pharmaceutical motifs with the utilization of 4-amine substituted isatins and widespread terminal alkyne-derived propargyl alcs. Furthermore, the synthetic utility of the methodol. and mechanistic studies also were well presented.
ACS Catalysis published new progress about Alcohols, lower Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Product Details of C4H8O.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts