Das, Jagadish; Vellakkaran, Mari; Banerjee, Debasis published the artcile< Nickel-Catalyzed Alkylation of Ketone Enolates: Synthesis of Monoselective Linear Ketones>, Electric Literature of 5344-90-1, the main research area is ketone alc nickel monoselective alkylation catalyst; linear ketone preparation green chem.
Herein we have developed a Ni-catalyzed protocol for the synthesis of linear ketones. Aryl, alkyl, and heteroaryl ketones as well as alcs. yielded the monoselective ketones in up to 90% yield. The catalytic protocol was successfully applied in to a gram-scale synthesis. For a practical utility, applications of a steroid derivative, oleyl alc., and naproxen alc. were employed. Preliminary catalytic investigations involving the isolation of a Ni intermediate and defined Ni-H species as well as a series of deuterium-labeling experiments were performed.
Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Electric Literature of 5344-90-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts