Chen, Yong; Chen, Qi; Wang, Yuyu; Zhang, Qiang; Han, Qiuxia published the artcile< Fluorocarbon-assisted surface orientation of N-halamine groups on cellulose in supercritical CO2: An effective and eco-friendly approach for developing higher biocidability>, Safety of But-3-en-1-ol, the main research area is surface orientation halamine polysiloxane cellulose supercritical carbon dioxide; biocidal halamine polysiloxane coating cotton textile antibacterial.
Preferential segregation of N-halamine structure to top surface to better contact with bacteria is demonstrated to be an effective tactic for achievement of higher biocidability. 5-Allylbarbituric acid and its fluorinated derivative, formed by sacrificing a imide hydrogen to tether a 4-perfluorohexylbutyl segment via nucleophilic substitution, were synthesized and sep. attached to (50% methylhydrosiloxane)-dimethylsiloxane block copolymer (P(MHS-DMS)) via hydrosilylation. Chlorination of N-H bonds originating from barbituric acid produced two N-halamine polysiloxanes that were interpenetrated into cellulose to form coatings with similar morphol. and thickness. Although containing ∼50% less total content of chlorine than its nonfluorinated counterpart, polysiloxane with fluorinated pendants exerted faster inactivation against Staphylococcus aureus and Escherichia coli due to the orientation of its N-halamine groups on top surface with the assistance of the low-surface-tension 4-perfluorohexylbutyl segment as verified by depth profiling using angle-dependent XPS (ADXPS). Design biocide with proper surface segregation ability therefore paves a new way for improved antibacterial efficacy. The stability and rechargeability of the biocidability of the coatings are satisfactory under washing cycles, UV irrigation, and storage.
Applied Surface Science published new progress about Antibacterial agents. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Safety of But-3-en-1-ol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts