Chen, Jieping; Ying, Jiale; Lu, Zhan published the artcile< Cobalt-catalyzed branched selective hydroallylation of terminal alkynes>, SDS of cas: 10602-04-7, the main research area is branched skipped diene preparation regioselective; terminal alkyne allylic electrophile Markovnikov hydroallylation cobalt catalyst.
Here, authors reported a cobalt-hydride-catalyzed Markovnikov-type hydroallylation of terminal alkynes with allylic electrophile to access valuable and branched skipped dienes (1,4-dienes) with good regioselectivity. This operationally simple protocol exhibits excellent functional group tolerance and exceptional substrate scope. The reactions could be carried out in gram-scale with TON (turn over number) up to 1160, and the products could be easily derivatized. The preliminary mechanism of electrophilic allylation of α-selective cobalt alkenyl intermediate was proposed based on deuterium labeling experiment and kinetic studies.
Nature Communications published new progress about Alkadienes Role: SPN (Synthetic Preparation), PREP (Preparation) (1,4-). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, SDS of cas: 10602-04-7.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts